Healthy diet reduces risk of cardiovascular disease by a third in over-40s

Men and women who adapt their daily diet to meet current UK dietary guidelines could reduce their risk of a heart attack or a stroke by up to a third.
In the randomized controlled trial, researchers measured the blood pressure, vascular function and CVD risk factors (such as cholesterol) in 162 healthy non-smoking men and women (aged 40-70 years) who followed a traditional British diet (control group) or an adapted one over a twelve-week period. Those on the modified diet ate oily fish once a week, more fruit and vegetables, replaced refined with wholegrain cereals, swapped high-fat dairy products and meats for low-fat alternatives, and restricted their intake of added sugar and salt. Participants were asked to replace cakes and cookies with fruit and nuts and were also supplied with cooking oils and spreads high in monounsaturated fat.
Adherence to the dietary advice was confirmed both with dietary records and by measuring specific biomarkers in the participants' blood and urine. The latter indicated an increase in potassium and fibre intake in the dietary group along with a drop in sodium (salt) and saturated fat and added sugar intake. However, total sugar intake remained unchanged owing to the increase in sugar intake from fruit.
The average body weight in the group who followed the modified diet fell by 1.3 kg whilst that in the control group rose by 0.6 kg after 12 weeks, resulting in an overall difference in weight of 1.9 kg between the two groups; the equivalent difference in Body Mass Index (BMI) was 0.7 between the groups. Waist circumference was 1.7 cm lower in the dietary group compared to the control group.
Significant falls in systolic blood pressure/diastolic blood pressure of 4.2/2.5 mm Hg for daytime and 2.9/1.9 mm Hg for night time were measured in the dietary group compared with the control group; the average heart rate was found to have lowered by 1.8 beats per minute. Levels of cholesterol also fell by 8%, although changes in the ratio of total cholesterol to high-density cholesterol were modest compared with the effects of drugs such as statins. No significant change was recorded in markers for insulin sensitivity, which predicts the risk of developing type 2 diabetes. Overall, the study concluded that healthy men and women aged 40 and over who adapt their daily diet to meet current UK dietary guidelines reduce their risk of heart disease by up to a third.